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Remdesivir is not yet licensed or approved anywhere globally and has not been demonstrated to be safe or effective for the treatment of the COVID-19.
Aruna subramanian trial#
"We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing," it said.
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The pharma company also said that it is also aware of positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of the investigational antiviral Remdesivir for the treatment of the COVID-19.
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The White House described the development as "quite good news". "Certainly, it's a positive it's a very positive event," Trump told reporters in response to a question on the latest result of the clinical trial of Remdesivir. As honey is one of the ingredients used in daily life, honey can also be used in chemoprevention against colon cancer.The California-based pharma company Gilead Sciences said that the preliminary results showed that 50 per cent of the COVID-19 patients treated with a 5-day dosage of Remdesivir improved and more than half were discharged from the hospital within two weeks.Ī phase three clinical trial is said to be the final step in the process of drug approval. This review also emphasis the need of numerous studies that are needed to be initiated to explore the anticancer effect of crude honey specifically. Various, in vitro experiments done are enlisted. In our review, we highlight the effect of honey and its phenolic constituents against the colon cancer cells. As colorectal cancer is more prone to the diet consumed, scientists have explored many dietary compounds to treat this particular type of cancer. The standard chemotherapeutic agents are usually noneffective in the latter stages of cancer. Practical ApplicationĬolon cancer is the third largest cause of cancer death worldwide. This review promulgates honey and its phytochemicals as candidates in colon cancer prevention. It is high time for scientists to initiate more trails using honey and its phytochemicals against some immune-deficient animal models of colon cancer and in low- and high-risk human individuals to validate honey as a mighty sword against colon cancer. Changes like activation of caspase-3, caspase-8, polyadenosine diphosphate-ribose polymerase cleavage, boost in ROS level activating mitochondrial pathway, lipid layer breakage, DNA fragmentation, increase of G0/G1 phase cells, up-regulation of Bax regulators and p53 dependent apoptosis are significant. Honey and its phytochemicals are found to inhibit the cancer growth. This work illustrates antiproliferative effects of honey and its phytochemicals against colorectal cancer to limelight. Diets rich in phenolic constituents are associated in eradicating various noncommunicable diseases including cancer. Among them, colorectal cancer is linked with diet as the epithelial cells of colon and rectum come in direct contact with diet. Cancer is one of the leading causes of death worldwide.